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Krüppel-like Factor 4 Inhibits Epithelial-to-Mesenchymal Transition through Regulation of E-cadherin Gene Expression

The Krüppel-like factor 4 (KLF4) is a transcriptional regulator of proliferation and differentiation in epithelial cells, both during development and tumorigenesis. Although KLF4 functions as a tumor suppressor in several tissues, including the colon, the role of KLF4 in breast cancer is less clear....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yori, Jennifer L., Johnson, Emhonta, Zhou, Guangjin, Jain, Mukesh K., Keri, Ruth A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878056/
https://ncbi.nlm.nih.gov/pubmed/20356845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.114546
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