Glutathionylation of Adenine Nucleotide Translocase Induced by Carbon Monoxide Prevents Mitochondrial Membrane Permeabilization and Apoptosis

The present work demonstrates the ability of CO to prevent apoptosis in a primary culture of astrocytes. For the first time, the antiapoptotic behavior can be clearly attributed to the inhibition of mitochondrial membrane permeabilization (MMP), a key event in the intrinsic apoptotic pathway. In iso...

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Bibliographic Details
Main Authors: Queiroga, Cláudia S. F., Almeida, Ana S., Martel, Cécile, Brenner, Catherine, Alves, Paula M., Vieira, Helena L. A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878049/
https://ncbi.nlm.nih.gov/pubmed/20348099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.065052
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