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Protein Kinase RNA/FADD/Caspase-8 Pathway Mediates the Proapoptotic Activity of the RNA-binding Protein Human Antigen R (HuR)

The RNA-binding protein human antigen R (HuR) has been implicated in apoptosis in multiple ways. Several studies have shown that in response to a variety of stresses HuR promotes the expression of proapoptotic mRNAs, whereas others reported its regulatory effect on antiapoptotic messages. We recentl...

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Detalhes bibliográficos
Main Authors: von Roretz, Christopher, Gallouzi, Imed-Eddine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878037/
https://ncbi.nlm.nih.gov/pubmed/20353946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.087320
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