A Common Substrate Recognition Mode Conserved between Katanin p60 and VPS4 Governs Microtubule Severing and Membrane Skeleton Reorganization

Katanin p60 (kp60), a microtubule-severing enzyme, plays a key role in cytoskeletal reorganization during various cellular events in an ATP-dependent manner. We show that a single domain isolated from the N terminus of mouse katanin p60 (kp60-NTD) binds to tubulin. The solution structure of kp60-NTD...

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Detalhes bibliográficos
Main Authors: Iwaya, Naoko, Kuwahara, Yohta, Fujiwara, Yoshie, Goda, Natsuko, Tenno, Takeshi, Akiyama, Kohei, Mase, Shogo, Tochio, Hidehito, Ikegami, Takahisa, Shirakawa, Masahiro, Hiroaki, Hidekazu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878028/
https://ncbi.nlm.nih.gov/pubmed/20339000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.108365
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