Sonic hedgehog is a critical mediator of erythropoietin-induced cardiac protection in mice

Erythropoietin reportedly has beneficial effects on the heart after myocardial infarction, but the underlying mechanisms of these effects are unknown. We here demonstrate that sonic hedgehog is a critical mediator of erythropoietin-induced cardioprotection in mice. Treatment of mice with erythropoie...

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Detalhes bibliográficos
Main Authors: Ueda, Kazutaka, Takano, Hiroyuki, Niitsuma, Yuriko, Hasegawa, Hiroshi, Uchiyama, Raita, Oka, Toru, Miyazaki, Masaru, Nakaya, Haruaki, Komuro, Issei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877931/
https://ncbi.nlm.nih.gov/pubmed/20484812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39896
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