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Sonic hedgehog is a critical mediator of erythropoietin-induced cardiac protection in mice

Erythropoietin reportedly has beneficial effects on the heart after myocardial infarction, but the underlying mechanisms of these effects are unknown. We here demonstrate that sonic hedgehog is a critical mediator of erythropoietin-induced cardioprotection in mice. Treatment of mice with erythropoie...

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Autores principales: Ueda, Kazutaka, Takano, Hiroyuki, Niitsuma, Yuriko, Hasegawa, Hiroshi, Uchiyama, Raita, Oka, Toru, Miyazaki, Masaru, Nakaya, Haruaki, Komuro, Issei
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877931/
https://ncbi.nlm.nih.gov/pubmed/20484812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39896
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