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Smart Hydrogel Particles: Biomarker Harvesting: One-step affinity purification, size exclusion, and protection against degradation

Disease-associated blood biomarkers exist in exceedingly low concentrations within complex mixtures of high-abundance proteins such as albumin. We have introduced an affinity bait molecule into N-isopropylacrylamide to produce a particle that will perform three independent functions within minutes,...

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Detalles Bibliográficos
Main Authors: Luchini, Alessandra, Geho, David H., Bishop, Barney, Tran, Duy, Xia, Cassandra, Dufour, Robert, Jones, Clint, Espina, Virginia, Patanarut, Alexis, Zhu, Weidong, Ross, Mark, Tessitore, Alessandra, Petricoin, Emanuel, Liotta, Lance A.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877922/
https://ncbi.nlm.nih.gov/pubmed/18076201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl072174l
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