Significance of the Fanconi Anemia FANCD2 Protein in Sporadic and Metastatic Human Breast Cancer

FANCD2, a pivotal protein in the Fanconi anemia and BRCA pathway/network, is monoubiquitylated in the nucleus in response to DNA damage. This study examines the subcellular location and relationship with prognostic factors and patient survival of FANCD2 in breast cancer. Antibodies to FANCD2 were us...

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Autors principals: Rudland, Philip S., Platt-Higgins, Angela M., Davies, Lowri M., de Silva Rudland, Suzete, Wilson, James B., Aladwani, Abdulaziz, Winstanley, John H.R., Barraclough, Dong L., Barraclough, Roger, West, Christopher R., Jones, Nigel J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877854/
https://ncbi.nlm.nih.gov/pubmed/20363922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090779
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