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Pathogenesis of Chronic Wasting Disease in Cervidized Transgenic Mice

Chronic wasting disease (CWD) is a fatal, endemic prion disease of wild and captive cervids, including deer, elk, and moose. Typical of prion diseases, CWD is characterized by the conversion of the native, protease-sensitive protein PrP(C) to a protease-resistant isoform, denoted as PrP(RES). Here w...

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Библиографические подробности
Главные авторы: Seelig, Davis M., Mason, Gary L., Telling, Glenn C., Hoover, Edward A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877840/
https://ncbi.nlm.nih.gov/pubmed/20395435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090710
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