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Emx2 and early hair cell development in the mouse inner ear

Emx2 is a homeodomain protein that plays a critical role in inner ear development. Homozygous null mice die at birth with a range of defects in the CNS, renal system and skeleton. The cochlea is shorter than normal with about 60% fewer auditory hair cells. It appears to lack outer hair cells and som...

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Detalhes bibliográficos
Main Authors: Holley, Matthew, Rhodes, Charlotte, Kneebone, Adam, Herde, Michel K., Fleming, Michelle, Steel, Karen P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877772/
https://ncbi.nlm.nih.gov/pubmed/20152827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.02.004
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