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Isoflurane Causes Greater Neurodegeneration than an Equivalent Exposure of Sevoflurane in the Developing Brain of Neonatal Mice

BACKGROUND: We hypothesized that isoflurane has a greater potency to induce neurodegeneration than sevoflurane in the developing brains of neonatal mice based on our previous studies in cell culture. METHODS: We treated 7-day-old mice with either 0.75% isoflurane or 1.1% sevoflurane (~0.5 Minimum Al...

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Main Authors: Liang, Ge, Ward, Christopher, Peng, Jun, Zhao, Yifan, Huang, Baosheng, Wei, Huafeng
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877765/
https://ncbi.nlm.nih.gov/pubmed/20460994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181d94da5
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