Aging and Chronic Sun Exposure Cause Distinct Epigenetic Changes in Human Skin

Epigenetic changes are widely considered to play an important role in aging, but experimental evidence to support this hypothesis has been scarce. We have used array-based analysis to determine genome-scale DNA methylation patterns from human skin samples and to investigate the effects of aging, chr...

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Bibliografiske detaljer
Main Authors: Grönniger, Elke, Weber, Barbara, Heil, Oliver, Peters, Nils, Stäb, Franz, Wenck, Horst, Korn, Bernhard, Winnefeld, Marc, Lyko, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877750/
https://ncbi.nlm.nih.gov/pubmed/20523906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000971
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