Perforin Expression Directly Ex Vivo by HIV-Specific CD8(+) T-Cells Is a Correlate of HIV Elite Control

Many immune correlates of CD8(+) T-cell-mediated control of HIV replication, including polyfunctionality, proliferative ability, and inhibitory receptor expression, have been discovered. However, no functional correlates using ex vivo cells have been identified with the known ability to cause the di...

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Hauptverfasser: Hersperger, Adam R., Pereyra, Florencia, Nason, Martha, Demers, Korey, Sheth, Prameet, Shin, Lucy Y., Kovacs, Colin M., Rodriguez, Benigno, Sieg, Scott F., Teixeira-Johnson, Leia, Gudonis, Debbie, Goepfert, Paul A., Lederman, Michael M., Frank, Ian, Makedonas, George, Kaul, Rupert, Walker, Bruce D., Betts, Michael R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877741/
https://ncbi.nlm.nih.gov/pubmed/20523897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000917
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