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Competition of Escherichia coli DNA Polymerases I, II and III with DNA Pol IV in Stressed Cells

Escherichia coli has five DNA polymerases, one of which, the low-fidelity Pol IV or DinB, is required for stress-induced mutagenesis in the well-studied Lac frameshift-reversion assay. Although normally present at ∼200 molecules per cell, Pol IV is recruited to acts of DNA double-strand-break repair...

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Detalhes bibliográficos
Main Authors: Hastings, P. J., Hersh, Megan N., Thornton, P. C., Fonville, Natalie C., Slack, Andrew, Frisch, Ryan L., Ray, Mellanie P., Harris, Reuben S., Leal, Suzanne M., Rosenberg, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877720/
https://ncbi.nlm.nih.gov/pubmed/20523737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010862
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