A complement receptor-1 polymorphism with high frequency in malaria endemic regions of Asia but not Africa

Complement receptor-1 (CR1) is a ligand for rosette formation, a phenomenon associated with cerebral malaria (CM). Binding is dependent on erythrocyte CR1 copy number. In Caucasians, low CR1 expressors have two linked mutations. We determined the Q981H and HindIII RFLP distribution in differing popu...

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Hlavní autoři: Thomas, BN, Donvito, B, Cockburn, I, Fandeur, T, Rowe, JA, Cohen, JHM, Moulds, JM
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877660/
https://ncbi.nlm.nih.gov/pubmed/15578041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gene.6364150
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