α-Synuclein Delays Endoplasmic Reticulum (ER)-to-Golgi Transport in Mammalian Cells by Antagonizing ER/Golgi SNAREs

Toxicity of human α-synuclein when expressed in simple organisms can be suppressed by overexpression of endoplasmic reticulum (ER)-to-Golgi transport machinery, suggesting that inhibition of constitutive secretion represents a fundamental cause of the toxicity. Whether similar inhibition in mammals...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Thayanidhi, Nandhakumar, Helm, Jared R., Nycz, Deborah C., Bentley, Marvin, Liang, Yingjian, Hay, Jesse C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2010
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877643/
https://ncbi.nlm.nih.gov/pubmed/20392839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-09-0801
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky