Daily Acyclovir Delays HIV-1 Disease Progression Among HIV-1/HSV-2 Dually-Infected Persons: A Randomized Trial

BACKGROUND: Well-tolerated medications that slow HIV-1 disease progression and delay initiation of antiretroviral therapy (ART) are needed. Most HIV-1-infected persons are dually-infected with herpes simplex virus type 2 (HSV-2). Daily HSV-2 suppression reduces plasma HIV-1 levels, but whether HSV-2...

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Main Authors: Lingappa, Jairam R., Baeten, Jared M., Wald, Anna, Hughes, James P., Thomas, Katherine K., Mujugira, Andrew, Mugo, Nelly, Bukusi, Elizabeth A., Cohen, Craig R., Katabira, Elly, Ronald, Allan, Kiarie, James, Farquhar, Carey, Stewart, Grace John, Makhema, Joseph, Essex, Myron, Were, Edwin, Fife, Kenneth H., de Bruyn, Guy, Gray, Glenda E., McIntyre, James, Manongi, Rachel, Kapiga, Saidi, Coetzee, David, Allen, Susan, Inambao, Mubiana, Kayitenkore, Kayitesi, Karita, Etienne, Kanweka, William, Delany, Sinead, Rees, Helen, Vwalika, Bellington, Magaret, Amalia, Wang, Richard S., Kidoguchi, Lara, Barnes, Linda, Ridzon, Renee, Corey, Lawrence, Celum, Connie
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877592/
https://ncbi.nlm.nih.gov/pubmed/20153888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(09)62038-9
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