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Natural selection drives the accumulation of amino acid tandem repeats in human proteins

Amino acid tandem repeats are found in a large number of eukaryotic proteins. They are often encoded by trinucleotide repeats and exhibit high intra- and interspecies size variability due to the high mutation rate associated with replication slippage. The extent to which natural selection is importa...

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Detalhes bibliográficos
Main Authors: Mularoni, Loris, Ledda, Alice, Toll-Riera, Macarena, Albà, M. Mar
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877571/
https://ncbi.nlm.nih.gov/pubmed/20335526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.101261.109
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