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A Novel Method to Detect Proteins Evolving at Correlated Rates: Identifying New Functional Relationships between Coevolving Proteins

Interacting proteins evolve at correlated rates, possibly as the result of evolutionary pressures shared by functional groups and/or coevolution between interacting proteins. This evolutionary signature can be exploited to learn more about protein networks and to infer functional relationships betwe...

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Autors principals: Clark, Nathaniel L., Aquadro, Charles F.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877527/
https://ncbi.nlm.nih.gov/pubmed/20044587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msp324
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