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Divergent Oriented Synthesis For the Design of Reagents for Protein Conjugation

Instead of using diversity oriented syntheses (DOS) to obtain compounds with biological activities, we employed the DOS method to efficiently obtain multifunctional single attachment point (MSAP) reagents for the conjugation to proteins. Acid insensitive functional groups (chelators, fluorochromes)...

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Detalhes bibliográficos
Main Authors: Garanger, Elisabeth, Blois, Joseph, Hilderbrand, Scott A., Shao, Fangwei, Josephson, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877490/
https://ncbi.nlm.nih.gov/pubmed/19928910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cc900141b
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