Age-related changes in neural volume and microstructure associated with interleukin-6 are ameliorated by a calorie-restricted diet in old rhesus monkeys

Systemic levels of proinflammatory cytokines such as interleukin-6 (IL-6) increase in old age and may contribute to neural atrophy in humans. We investigated IL-6 associations with age in T1-weighted segments and microstructural diffusion indices using MRI in aged rhesus monkeys (Macaca mulatta). Fu...

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Detalhes bibliográficos
Main Authors: Willette, AA, Bendlin, BB, McLaren, DG, Canu, E, Kastman, EK, Kosmatka, KJ, Xu, G, Field, AS, Alexander, AL, Colman, RJ, Weindruch, RH, Coe, CL, Johnson, SC
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877377/
https://ncbi.nlm.nih.gov/pubmed/20298794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2010.03.015
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