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Amphipathic Helical Cationic Antimicrobial Peptides Promote Rapid Formation of Crystalline States in the Presence of Phosphatidylglycerol: Lipid Clustering in Anionic Membranes

Five AHCAPs exhibiting a broad-spectrum of antimicrobial activity, were examined with regard to their action in lipid mixtures with two anionic lipids, PG and CL. We find that all of the peptides studied were capable of promoting the formation of crystalline phases of DMPG in mixtures of DMPG and CL...

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Detalhes bibliográficos
Main Authors: Epand, Raquel F., Maloy, Lee, Ramamoorthy, Ayyalusamy, Epand, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877319/
https://ncbi.nlm.nih.gov/pubmed/20513400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.002
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