Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease

Alzheimer's disease (AD) is a complex disease that is likely influenced by many genetic and environmental factors. Citing evidence that iron may play a role in AD pathology, Robson et al. (2004) reported that epistatic interaction between rs1049296 (P589S) and rs1800562 (C282Y) in the hemochrom...

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Bibliographic Details
Main Authors: Kauwe, JSK, Bertelsen, S, Mayo, K, Cruchaga, C, Abraham, R, Hollingworth, P, Harold, D, Owen, MJ, Williams, J, Lovestone, S, Morris, JC, Goate, AM
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877151/
https://ncbi.nlm.nih.gov/pubmed/20029940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.31053
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