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HDAC6 Regulates Mitochondrial Transport in Hippocampal Neurons
BACKGROUND: Tubulin is a major substrate of the cytoplasmic class II histone deacetylase HDAC6. Inhibition of HDAC6 results in higher levels of acetylated tubulin and enhanced binding of the motor protein kinesin-1 to tubulin, which promotes transport of cargoes along microtubules. Microtubule-depen...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877100/ https://ncbi.nlm.nih.gov/pubmed/20520769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010848 |
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