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Spatio-temporal modeling of signaling protein recruitment to EGFR

BACKGROUND: A stochastic simulator was implemented to study EGFR signal initiation in 3D with single molecule detail. The model considers previously unexplored contributions to receptor-adaptor coupling, such as receptor clustering and diffusive properties of both receptors and binding partners. The...

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Detalhes bibliográficos
Main Authors: Hsieh, Ming-yu, Yang, Shujie, Raymond-Stinz, Mary Ann, Edwards, Jeremy S, Wilson, Bridget S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877007/
https://ncbi.nlm.nih.gov/pubmed/20459599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-57
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