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Principles of membrane protein interactions with annular lipids deduced from aquaporin-0 2D crystals

We have previously described the interactions of aquaporin-0 (AQP0) with dimyristoyl phosphatidylcholine (DMPC) lipids. We have now determined the 2.5 Å structure of AQP0 in two-dimensional (2D) crystals formed with Escherichia coli polar lipids (EPLs), which differ from DMPC both in headgroups and...

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Detalhes bibliográficos
Main Authors: Hite, Richard K, Li, Zongli, Walz, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876970/
https://ncbi.nlm.nih.gov/pubmed/20389283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.68
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