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Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe
Nonsense-mediated mRNA decay (NMD) is a translation-linked process that destroys mRNAs with premature translation termination codons (PTCs). In mammalian cells, NMD is also linked to pre-mRNA splicing, usually PTCs trigger strong NMD only when positioned upstream of at least one intron. The exon jun...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876954/ https://ncbi.nlm.nih.gov/pubmed/20360683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.48 |
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