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A Realistic Large-Scale Model of the Cerebellum Granular Layer Predicts Circuit Spatio-Temporal Filtering Properties

The way the cerebellar granular layer transforms incoming mossy fiber signals into new spike patterns to be related to Purkinje cells is not yet clear. Here, a realistic computational model of the granular layer was developed and used to address four main functional hypotheses: center-surround organ...

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Autori principali: Solinas, Sergio, Nieus, Thierry, D'Angelo, Egidio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Research Foundation 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876868/
https://ncbi.nlm.nih.gov/pubmed/20508743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2010.00012
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