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S-Adenosylhomocysteine Hydrolase (AHCY) Deficiency: Two Novel Mutations with Lethal Outcome

This paper reports studies of two novel, allelic missense mutations found in the S-adenosylhomocysteine hydrolase (AHCY) gene from a new case of AHCY deficiency in an infant girl who died at age four months. The mutations lead to replacement of arginine with cysteine (p.Arg49Cys) and aspartic acid w...

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Detalhes bibliográficos
Main Authors: Vugrek, Oliver, Belužić, Robert, Nakić, Nikolina, Mudd, S. Harvey
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876820/
https://ncbi.nlm.nih.gov/pubmed/19177456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.20985
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