تحميل...
Depletion of the Programmed Death-1 Receptor Completely Reverses Established Clonal Anergy in CD4(+) T Lymphocytes via an Interleukin-2-Dependent Mechanism
Recent studies have implicated the cell surface receptor Programmed Death-1 (PD-1) in numerous models of T cell anergy, though the specific mechanisms by which the PD-1 signal maintains tolerance is not clear. We demonstrate that the depletion of PD-1 with siRNA results in a complete reversal of clo...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
2009
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876711/ https://ncbi.nlm.nih.gov/pubmed/19230866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2009.01.008 |
| الوسوم: |
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