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Japanese Encephalitis Virus Utilizes the Canonical Pathway To Activate NF-κB but It Utilizes the Type I Interferon Pathway To Induce Major Histocompatibility Complex Class I Expression in Mouse Embryonic Fibroblasts

Flaviviruses have been shown to induce cell surface expression of major histocompatibility complex class I (MHC-I) through the activation of NF-κB. Using IKK1(−/−), IKK2(−/−), NEMO(−/−), and IKK1(−/−) IKK2(−/−) double mutant as well as p50(−/−) RelA(−/−) cRel(−/−) triple mutant mouse embryonic fibro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Abraham, Sojan, Nagaraj, Ashwini Sankrepatna, Basak, Soumen, Manjunath, Ramanathapuram
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876612/
https://ncbi.nlm.nih.gov/pubmed/20357096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02250-09
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