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Glycoprotein D of Bovine Herpesvirus 5 (BoHV-5) Confers an Extended Host Range to BoHV-1 but Does Not Contribute to Invasion of the Brain

Bovine herpesvirus 1 (BoHV-1) and BoHV-5 are closely related pathogens of cattle, but only BoHV-5 is considered a neuropathogen. We engineered intertypic gD exchange mutants with BoHV-1 and BoHV-5 backbones in order to address their in vitro and in vivo host ranges, with particular interest in invas...

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Main Authors: Gabev, Evgeni, Tobler, Kurt, Abril, Carlos, Hilbe, Monika, Senn, Claudia, Franchini, Marco, Campadelli-Fiume, Gabriella, Fraefel, Cornel, Ackermann, Mathias
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876591/
https://ncbi.nlm.nih.gov/pubmed/20219909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00228-10
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