High-Resolution Cryo-Electron Microscopy Structures of Murine Norovirus 1 and Rabbit Hemorrhagic Disease Virus Reveal Marked Flexibility in the Receptor Binding Domains

Our previous structural studies on intact, infectious murine norovirus 1 (MNV-1) virions demonstrated that the receptor binding protruding (P) domains are lifted off the inner shell of the virus. Here, the three-dimensional (3D) reconstructions of recombinant rabbit hemorrhagic disease virus (rRHDV)...

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Main Authors: Katpally, Umesh, Voss, Neil R., Cavazza, Tommaso, Taube, Stefan, Rubin, John R., Young, Vivienne L., Stuckey, Jeanne, Ward, Vernon K., Virgin, Herbert W., Wobus, Christiane E., Smith, Thomas J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Structure and Assembly
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876586/
https://ncbi.nlm.nih.gov/pubmed/20335264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00314-10
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