Temperature-Induced Changes in the Lipopolysaccharide of Yersinia pestis Affect Plasminogen Activation by the Pla Surface Protease

The Pla surface protease of Yersinia pestis activates human plasminogen and is a central virulence factor in bubonic and pneumonic plague. Pla is a transmembrane β-barrel protein and member of the omptin family of outer membrane proteases which require bound lipopolysaccharide (LPS) to be proteolyti...

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Main Authors: Suomalainen, Marjo, Lobo, Leandro Araujo, Brandenburg, Klaus, Lindner, Buko, Virkola, Ritva, Knirel, Yuriy A., Anisimov, Andrey P., Holst, Otto, Korhonen, Timo K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Molecular Pathogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876559/
https://ncbi.nlm.nih.gov/pubmed/20368351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01329-09
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