Mitogen-Activated Protein Kinase Phosphatase 2 Regulates the Inflammatory Response in Sepsis

Sepsis results from a dysregulation of the regulatory mechanisms of the pro- and anti-inflammatory response to invading pathogens. The mitogen-activated protein (MAP) kinase cascades are key signal transduction pathways involved in the cellular production of cytokines. The dual-specific phosphatase...

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Bibliographic Details
Main Authors: Cornell, Timothy T., Rodenhouse, Paul, Cai, Qing, Sun, Lei, Shanley, Thomas P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876557/
https://ncbi.nlm.nih.gov/pubmed/20351138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00018-10
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