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Francisella tularensis ΔpyrF Mutants Show that Replication in Nonmacrophages Is Sufficient for Pathogenesis In Vivo

The pathogenesis of Francisella tularensis has been associated with this bacterium's ability to replicate within macrophages. F. tularensis can also invade and replicate in a variety of nonphagocytic host cells, including lung and kidney epithelial cells and hepatocytes. As uracil biosynthesis...

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Hlavní autoři: Horzempa, Joseph, O'Dee, Dawn M., Shanks, Robert M. Q., Nau, Gerard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876533/
https://ncbi.nlm.nih.gov/pubmed/20385757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00134-10
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