Safety and Pharmacokinetics of Single Intravenous Dose of MGAWN1, a Novel Monoclonal Antibody to West Nile Virus

West Nile Virus (WNV) is a neurotropic flavivirus that can cause debilitating diseases, such as encephalitis, meningitis, or flaccid paralysis. We report the safety, pharmacokinetics, and immunogenicity of a recombinant humanized monoclonal antibody (MGAWN1) targeting the E protein of WNV in a phase...

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Detalhes bibliográficos
Main Authors: Beigel, John H., Nordstrom, Jeffrey L., Pillemer, Stanley R., Roncal, Cory, Goldwater, D. Ronald, Li, Hua, Holland, P. Chris, Johnson, Syd, Stein, Kathryn, Koenig, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876374/
https://ncbi.nlm.nih.gov/pubmed/20350945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01178-09
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