Ovine reference materials and assays for prion genetic testing

BACKGROUND: Genetic predisposition to scrapie in sheep is associated with several variations in the peptide sequence of the prion protein gene (PRNP). DNA-based tests for scoring PRNP codons are essential tools for eradicating scrapie and for evaluating rare alleles for increased resistance to disea...

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Main Authors: Heaton, Michael P, Leymaster, Kreg A, Kalbfleisch, Theodore S, Freking, Brad A, Smith, Timothy PL, Clawson, Michael L, Laegreid, William W
格式: Artigo
語言:Inglês
出版: BioMed Central 2010
主題:
Methodology article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876147/
https://ncbi.nlm.nih.gov/pubmed/20433741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-6-23
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