MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients

BACKGROUND: MUC1 protein is highly expressed in lung cancer. The cytoplasmic domain of MUC1 (MUC1-CD) induces tumorigenesis and resistance to DNA-damaging agents. We characterized MUC1-CD-induced transcriptional changes and examined their significance in lung cancer patients. METHODS: Using DNA micr...

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Détails bibliographiques
Auteurs principaux: MacDermed, Dhara M, Khodarev, Nikolai N, Pitroda, Sean P, Edwards, Darrin C, Pelizzari, Charles A, Huang, Lei, Kufe, Donald W, Weichselbaum, Ralph R
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876055/
https://ncbi.nlm.nih.gov/pubmed/20459602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-3-16
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