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In vivo virus infection inhibits type I interferon production by plasmacytoid dendritic cells thereby facilitating opportunistic infections

Emerging in vitro and epidemiological studies indicate an association between virally-induced impaired type I interferon (IFN-I) production and enhanced susceptibility to opportunistic infections, which represent a major health problem. Here, we provide in vivo evidence that lymphocytic choriomening...

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Detalhes bibliográficos
Main Authors: Zuniga, Elina I, Liou, Li-Ying, Mack, Lauren, Mendoza, Marilyn, Oldstone, Michael BA
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875928/
https://ncbi.nlm.nih.gov/pubmed/18854241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.08.016
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