Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells

INTRODUCTION: This study was undertaken to determine whether the anti-osteoarthritis drug pentosan polysulfate (PPS) influenced mesenchymal precursor cell (MPC) proliferation and differentiation. METHODS: Human MPCs were maintained in monolayer, pellet or micromass cultures (MMC) for up to 10 days w...

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Autori principali: Ghosh, Peter, Wu, Jiehua, Shimmon, Susan, Zannettino, Andrew CW, Gronthos, Stan, Itescu, Silviu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875662/
https://ncbi.nlm.nih.gov/pubmed/20167057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2935
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