High-density lipoproteins downregulate CCL2 production in human fibroblast-like synoviocytes stimulated by urate crystals

INTRODUCTION: To investigate whether monosodium urate (MSU) crystals induce the production of CCL2 (monocyte chemoattractant protein-1; MCP-1) in human fibroblast-like synoviocytes (FLS) and whether this mechanism would be affected by high-density lipoproteins (HDL). METHODS: Human FLS isolated from...

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Main Authors: Scanu, Anna, Oliviero, Francesca, Gruaz, Lyssia, Sfriso, Paolo, Pozzuoli, Assunta, Frezzato, Federica, Agostini, Carlo, Burger, Danielle, Punzi, Leonardo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875657/
https://ncbi.nlm.nih.gov/pubmed/20149224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2930
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