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A pharmacogenetic model of naltrexone-induced attenuation of alcohol consumption in rhesus monkeys
BACKGROUND: Variation at the human μ-opioid receptor has been associated with alcohol abuse. The A118G (N40D) polymorphism in humans is functionally mimicked by the C77G (P26R) polymorphism in rhesus monkeys; both show similar in vitro influences on ligand binding and in vivo correlations with physi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875311/ https://ncbi.nlm.nih.gov/pubmed/20153935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2010.01.005 |
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