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VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis

VEGF is the key growth factor regulating arterial morphogenesis. However, molecular events involved in this process have not been elucidated. Synectin null mice demonstrate impaired VEGF signaling and a marked reduction in arterial morphogenesis. Here we show that this occurs due to delayed traffick...

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Bibliografiset tiedot
Päätekijät: Lanahan, Anthony A., Hermans, Karlien, Claes, Filip, Kerley-Hamilton, Joanna S., Zhuang, Zhen W., Giordano, Frank J., Carmeliet, Peter, Simons, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875289/
https://ncbi.nlm.nih.gov/pubmed/20434959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.02.016
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