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A Direct Role for Secretory Phospholipase A(2) and Lyso-Phosphatidylcholine in the Mediation of Lipopolysaccharide-induced Gastric Injury

BACKGROUND & AIMS: Endotoxemia from sepsis can injure the GI tract through mechanisms that have not been fully elucidated. We have shown that lipopolysaccharide (LPS) induces an increase in gastric permeability in parallel with the luminal appearance of secretory phospholipase A(2) (sPLA(2)) and...

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Detalhes bibliográficos
Main Authors: Dial, Elizabeth J., Tran, Duy M., Romero, Jimmy J., Zayat, Mayssa, Lichtenberger, Lenard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875268/
https://ncbi.nlm.nih.gov/pubmed/19940811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181cb9266
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