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Temporal and Spatial Regulation of V(D)J Recombination: Interactions of Extrinsic Factors with the RAG Complex

In the course of lymphoid development, V(D)J recombination is subject to stringent locus-specific and temporal regulation. These constraints are ultimately responsible for several features peculiar to lymphoid development, including the lineage specificity of antigen receptor assembly, allelic exclu...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Liu, Yun, Zhang, Li, Desiderio, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875152/
https://ncbi.nlm.nih.gov/pubmed/19731809
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