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Solid State (2)H NMR Analysis of Furanose Ring Dynamics in DNA Containing Uracil

DNA damage has been implicated in numerous human diseases, particularly cancer, and the aging process. Single-base lesions, such as uracil, in DNA can be cytotoxic or mutagenic and are recognized by a DNA glycosylase during the process of base excision repair. Increased dynamic properties in lesion-...

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Detalhes bibliográficos
Main Authors: Kinde-Carson, Monica N., Ferguson, Crystal, Oyler, Nathan A., Harbison, Gerard S., Meints, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875086/
https://ncbi.nlm.nih.gov/pubmed/20151717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp9091656
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