ALDH1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer

PURPOSE: To examine the role of cancer stem cells (CSCs) in mediating metastasis in Inflammatory breast cancer (IBC), and the association of these cells with patient outcome in this aggressive type of breast cancer. EXPERIMENTAL DESIGN: CSCs were isolated from SUM149 and MARY-X an IBC cell line and...

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Hauptverfasser: Charafe-Jauffret, Emmanuelle, Ginestier, Christophe, Iovino F, Flora, Tarpin, Carole, Diebel, Mark, Esterni, Benjamin, Houvenaeghel, Gilles, Extra, Jean-Marc, Bertucci, François, Jacquemier, Jocelyne, Xerri, Luc, Dontu, Gabriela, Stassi, Giorgio, Xiao, Yi, Barsky, Sanford H, Birnbaum, Daniel, Viens, Patrice, Wicha, Max S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874875/
https://ncbi.nlm.nih.gov/pubmed/20028757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1630
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