High frequency stimulation of the subthalamic nucleus evokes striatal dopamine release in a large animal model of human DBS neurosurgery

Subthalamic nucleus deep brain stimulation (STN DBS) ameliorates motor symptoms of Parkinson’s disease, but the precise mechanism is still unknown. Here, using a large animal (pig) model of human STN DBS neurosurgery, we utilized fast-scan cyclic voltammetry in combination with a carbon-fiber microe...

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Autori principali: Shon, Young-Min, Lee, Kendall H., Goerss, Stephan J., Kim, In Yong, Kimble, Chris, Van Gompel, Jamie J., Bennet, Kevin, Blaha, Charles D., Chang, Su-Youne
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874873/
https://ncbi.nlm.nih.gov/pubmed/20347936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.03.060
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