Ouabain attenuates cardiotoxicity induced by other cardiac steroids

BACKGROUND AND PURPOSE: All cardiac steroids have a similar structure, bind to and inhibit the ubiquitous transmembrane protein Na(+), K(+)-ATPase and increase the force of contraction of heart muscle. However, there are diverse biological responses to different cardiac steroids both at the cellular...

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Bibliographic Details
Main Authors: Nesher, M, Shpolansky, U, Viola, N, Dvela, M, Buzaglo, N, Ben-Ami, H Cohen, Rosen, H, Lichtstein, D
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2010
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874856/
https://ncbi.nlm.nih.gov/pubmed/20423344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00701.x
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