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Recognition, neutralization and clearance of target peptides in the blood stream of living mice by molecular imprinted polymer nanoparticles: a plastic antibody

[Image: see text] We report that simple, synthetic organic polymer nanoparticles (NPs) can capture and clear a target peptide toxin in the bloodstream of living mice. The protein-size polymer nanoparticles, with a binding affinity and selectivity comparable to natural antibodies, were prepared by co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hoshino, Yu, Koide, Hiroyuki, Urakami, Takeo, Kanazawa, Hiroaki, Kodama, Takashi, Oku, Naoto, Shea, Kenneth J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874824/
https://ncbi.nlm.nih.gov/pubmed/20420394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja102148f
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